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Initialtrials of HFOV used low lung volume strategies.This technique may be ideal for infants withestablished air leak syndromes but when infantswith RDS were studied, no pulmonary bene? tswere found with HFOV, and higher rates of IVHwere seen (The HIFI Study Group 1989 ). This formulation was administered orally to 2.3 million personsat high risk in an epidemic in a region affected by natural disasters. Mechanisms for the hypertriglyceridemic effect of marine omega-3fatty acids.